Top 10 Deadliest and Most Dangerous Viruses on the Earth

          1. 
Marburg Virus(MARV)

Ø  It
is members of the filovirus family and are characterized by hemorrhagic fever.

Ø  MARV
causes Marburg virus disease in humans in the form of viral hemorrhagic fever

Ø  Death
rate  of this  virus is as high as 90%

Ø  Host:
Bats (yet to be confirmed)

Ø  Treatment
: No
antiviral therapy or other vaccine exists  till yet

         2. 
Ebola virus (EV)

ü  Ebola virus disease (EVD), also known
as Ebola haemorrhagic fever, is a viral haemorrhagic fever of humans caused by
ebolaviruses

ü  Signs and symptoms: start between 2  days to 3 weeks like fever, sore throat,
muscular pain, and headaches.

ü   Death
rate : 25% to 90% average 50%

ü  Genetic material: single-stranded RNA

ü  Treatments: REGN-EB3 and mAb114  90% effective

ü  Host: Bats

         3.  Hantavirus(Hantavirus pulmonary syndrome (HPS)

• v  Hantavirus
  cause Hantavirus pulmonary syndrome in human
• v  Symptom
  : Hemorrhagic fever with renal syndrome
  (HFRS)
• v  Genetic material: three
  single-stranded, negative-sense RNA
• v  Death rate : 25% to 50 average
• v  Treatments: No available yet
• v  Host: Deer mouse (Peromyscus maniculatus)
• 
  

          4.  Middle East respiratory syndrome, or MERS

·        
Camel flu also known as  Middle East respiratory syndrome (MERS), ) is a viral
respiratory disease caused by a novel coronavirus ( MERS‐CoV) that was first
identified in the middle east (Saudi Arabia)
in 2012

·        
Symptoms:
Fever, Cough, Diarrhea and shortness of breath

·        
Death
rate : 35% to 40 %

·        
Genetic
materials: Single-stranded
RNA belonging to the genus betacoronavirus

·        
Host :
Camel

·        
Treatment:
Combination of antivirals drugs

         5.  Severe acute respiratory
syndrome((SARS)

Ø This virus  causes severe
acute respiratory syndrome(SARS)

Ø It can infect humans, bats, and palm civets.

Ø Genetic materials :
positive-sense, single-stranded
RNA virus

Ø  Death rate : 9 to 10 %

Ø  Treatment:

Ø  Primary Human receptor of the virus:
Angiotensin-converting
enzyme 2 (ACE2)

Ø  Treatment:
Combination of antiviral drugs

           6.  Japanese
encephalitis virus(JEV)

o  
Japanese encephalitis is a
mosquito-borne viral infection of the brain caused by the
Japanese encephalitis virus (JEV)

o  
Humans can get this disease  through mosquito bites that carries the virus

o  
Sign and symptoms:  headache, high fever, nausea, vomiting, stiff
neck,

spastic paralysis, confusion
and seizures

o  
Genetic material: positive
sense single-stranded RNA genome

o  
Death
rate : 10 % 30%

o  
Treatment
: No specific treatment for Japanese encephalitis

                7.    Lassa fever virus

                                               Morality rate  15 to   50%

            8.  Influenza: 

                                              Morality rate  10 to  40%

            9.  Dengue:

                                            Morality rate  2 to  20%

        10. SARS-CoV-2:

c                                                           Coronaviruses (COVID-19)

v Morality
rate  2 to  10%

v  SARS-CoV-2,
 also known as coronaviruses,

v  Disease caused by SARS-CoV-2 called COVID-19

v  Sign
and symptoms: fever, dry cough and shortness of breath, and the disease can
progress to pneumonia in severe cases.

v  Genetic
material: RNA viruses with relatively large genomes(29,891
nucleotides).

v  Host
: Not known yet.

v  Treatment:
Combination of antiviral drugs