Location: Agroscope, Nyon (future relocation to Posieux in 2026)

Start Date: 01 October 2025
Duration: 4 years (until 30.09.2029)
Affiliation: PhD School in Life Sciences, University of Geneva
Funding: Fully funded (100%)

PhD Research Focus: Molecular Microbiology & Yeast-Based Biocontrol

The PhD project centers on the biocontrol potential of the yeast Metschnikowia pulcherrima—a promising candidate in natural plant protection strategies. The research aims to unlock the molecular mechanisms behind its antifungal activity using state-of-the-art techniques in microbiology, genetics, and phytopathology.

You’ll be part of a forward-thinking team applying biotechnology to real-world challenges in sustainable agriculture and plant health.

Your Role & Responsibilities

As a PhD researcher, your tasks will include:

• Conducting fundamental and applied research in microbiology
• Performing advanced molecular techniques such as:
  • RNA sequencing (RNA-seq)
  • Transcriptomic analysis
  • CRISPR/Cas9-based gene editing
  • Whole genome sequencing
  • Biocontrol bioassays
• Analyzing complex experimental datasets
• Collaborating with interdisciplinary scientific teams
• Writing a high-impact PhD thesis and publishing in peer-reviewed journals

Candidate Profile: Who Should Apply?

Ideal candidates should meet the following criteria:

• Master’s degree (MSc) in Biology, Microbiology, Molecular Biology, or a related discipline
• Solid hands-on lab experience in microbiological or molecular techniques
• Familiarity with tools like cloning, PCR, DNA sequencing
• Passion for applied research in sustainable agriculture and biocontrol
• Strong communication skills in English, with knowledge of Swiss national languages (French/German/Italian) being an advantage

Research Objectives

Key goals of this PhD project include:

• Exploring pulcherrimin metabolism in Metschnikowia pulcherrima
• Genetic and functional characterization of mutant strains
• Comparative analysis with the model yeast Saccharomyces cerevisiae

The PhD will be supervised by Prof. Robbie Loewith at the University of Geneva, a leading expert in molecular biology and cellular signaling.

Why Choose Agroscope?

Agroscope is Switzerland’s national hub for agricultural and food research, working at the interface of science and society. As part of the Swiss Federal Department of Economic Affairs, Education and Research (EAER), Agroscope is committed to innovation in:

• Sustainable crop protection
• Environmental conservation
• Healthy food systems

Note: Agroscope’s current location in Nyon will move to Posieux in 2026.

How to Apply

Interested candidates are encouraged to prepare a strong application highlighting:

• Motivation for pursuing a PhD in microbial biocontrol
• Relevant academic and laboratory experience
• Language skills and collaborative mindset

Deadline: Apply as early as possible. Starting date is 01 October 2025 or by mutual agreement.

Launch Your Scientific Career in Switzerland

This is a rare opportunity to contribute to impactful research at the intersection of microbiology, plant pathology, and sustainable agriculture. With full funding, expert supervision, and access to world-class research facilities, this PhD program will provide you with the tools and experience to become a leader in your field.

Job Location

• Current Location: Agroscope, Zürich
• Planned Relocation: Schwerzenbach, Switzerland
• Start Date: 01 September 2025 or as agreed
• Contract Duration: Temporary (until 31 August 2028)
• Reference Code: JRQ$540-15362

Project Overview: Advancing Transgene-Free Genome Editing in Potatoes

This research project aims to develop climate-resilient potato varieties that are drought-tolerant and disease-resistant through transgene-free genome editing technologies. The project integrates advanced molecular biology, genome sequencing, and phenotypic analysis in both greenhouse and field environments.

Collaborate with world-renowned institutions including:

• Wageningen University, Netherlands
• Swedish University of Agricultural Sciences (SLU), Sweden

This is a unique opportunity to contribute to the future of sustainable crop development in Europe.

Key Responsibilities

As a postdoctoral researcher, you will:

• Design and implement targeted genome editing in potatoes
• Monitor editing events using real-time PCR and sequencing techniques
• Perform heat stress and disease resistance assays in greenhouses and field trials
• Conduct phenotypic assessments of GM potato field trials
• Collaborate with bioinformatics teams to analyze genomic and epigenomic effects
• Attend and present at international research consortium meetings

Candidate Profile: Who Should Apply?

Ideal candidates will have:

• A PhD in crop science, molecular breeding, plant biotechnology, or related field
• Hands-on experience in molecular biology, preferably with long-read sequencing
• A solid publication record in peer-reviewed international journals
• A collaborative mindset with the ability to work across diverse research teams
• Bonus: Experience in genomic analysis and bioinformatics
• Language Proficiency: English (mandatory) and at least one official Swiss language (preferred)

Why This Postdoc Matters: Sustainability & Innovation

Join a cutting-edge initiative shaping the future of climate-smart agriculture. This role offers the opportunity to:

• Contribute to transgene-free genome editing innovations
• Accelerate the breeding of climate-resilient crops
• Apply bioinformatics to monitor genome-wide editing impacts
• Help reduce the use of agrochemicals in European potato farming

About Agroscope – Excellence in Agricultural Research

Agroscope is the Swiss Federal Centre of Excellence for Agricultural Research, operating under the Federal Department of Economic Affairs, Education and Research (EAER). Agroscope focuses on:

• Food security
• Environmental sustainability
• Modern agricultural innovation

With a strong network of national and international collaborations, Agroscope supports science-driven solutions for sustainable food systems.

Project Location Details

• Current Site: Reckenholzstrasse 191, 8046 Zürich, Switzerland
• Future Site: 8603 Schwerzenbach, Switzerland (relocation planned mid-project)
• Principal Investigator: Dr. Etienne Bucher, Group Leader

How to Apply

Ready to make an impact in agricultural genomics?
Apply now through the official Agroscope application portal. Be sure to mention the Reference Code JRQ$540-15362 in your application.